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“Cancer cells grow in distinctive patterns that defy normal limitations.
That growth activity requires energy, and so cancer cells metabolize nutrients in different ways from the healthy cells around them. In an attempt to kill the tumor without killing the normally functioning cells, chemotherapy drugs target these pathways inside of cancer cells. This is notoriously difficult, expensive, and prone to toxic side effects that account for much of the suffering associated with the disease.
Now doctors are starting to think more about specific nutrients that feed tumor cells. That is, how what we eat affects how cancers grow—and whether there are ways to potentially “starve” cancer cells without leaving a person undernourished, or even hungry.
“For a long time, the prevailing thought was that altered metabolism in cancer cells was the result of genes and mutations that determined metabolism,” says Jason Locasale, a cancer biologist at Duke University. “Now, as we know, it’s a complex interaction of environment and genes, and one of the major factors at play is nutrition.””
JJ Editor's Picks
"The New York Times’ weekend exposé, based on hundreds of pages of leaked Communist Party documents, details the planning and deliberations behind the mass detention in reeducation camps of Muslims in China’s Xinjiang province, most of them..."
"Blaze Bernstein, age 19 at the time of his murder, loved to cook. Before he traveled back to his home in California for the 2017-’18 winter break, the University of Pennsylvania sophomore had been elected managing editor of a campus cooking..."
"Imagine for a moment that an alien astrophysicist on some distant but inhabited planet is trying to find out whether Earth is inhabited. If they were looking in the last 100 years, there would have been several unequivocal pieces of evidence..."
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"There is a growing feeling, among those who have the responsibility of managing large economies, that the discipline of economics is no longer fit for purpose. It is beginning to look like a science designed to solve problems that no longer exist."
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"The issue of Israel’s rights in the West Bank under international law, as simple as it sounds, conceals a complex and extensive web of historic, legal, military and political issues that, for many years, have engaged and continue to engage the..."
"You’re walking around and a thought occurs: “I should check my phone.” The phone comes out of your pocket. You type a message. Then your eyes remain glued to the screen, even when you walk across the street. We all do this kind of distracted..."