Best Of The Web
“A Chinese researcher recently disrupted the CCR5 gene, which builds a protein that acts as an entryway that HIV uses to gain entry to T-cells, allegedly creating the world’s first genetically engineered baby. Chinese officials moved swiftly to condemn the work, and rightly so. Gene-edited babies should probably always be prohibited, not because of fears of creating inequalities and advantaged “super babies,” but because of the reality that editing an embryo is not medically necessary. These modifications occur around conception rather than treating a suffering person—always involving introducing risk, and thus testing the age-old medical admonition of primum non nocere, meaning “first, to do no harm.”
I have argued previously that it is better to enforce national, rather than international, regulation of gene modification tools such as CRISPR-Cas9, since strong regulatory powers such as the FDA exist (swift action by the Chinese supports this claim). In fact, the FDA has so far chosen to regulate CRISPR technology as a drug, rather than a device, which gives it more control over specific applications and uses, while Congress excludes money in its spending bill from being used by the FDA to review applications for editing germ-line or heritable code. Nevertheless, there is no law in the U.S. that outlaws gene-edited babies.
I believe that most modern nations have adequate controls to regulate gene-modified babies, but it is important to explain why there will always be an ambiguous health benefit in creating GMO humans. Consider that disabling the CCR5 gene is not a new idea since U.S. biotech companies are already pursuing a strategy of using a form of gene modification to disrupt this gene to protect T cells from HIV infection. One important difference to this form of prophylactic gene therapy is that when applying it to living human patients a doctor can trade off the risk of the disease versus the tiny risks that gene modification tools could unintentionally alter other genes or damage functional DNA in a patient. In the case of a gene-modified baby, one is only adding the risk of inserting the CRISPR molecules, compared to a hypothetical health status of a person-to-be. The risk calculation is speculative at best.”
JJ Editor's Picks
"On Christmas Eve of 1966, Paddy Roy Bates, a retired British army major, drove a small boat with an outboard motor seven miles off the coast of England into the North Sea. He had sneaked out of his house in the middle of the night, inspired..."
"The book that changed lecturer, activist, and current presidential candidate Marianne Williamson’s life, A Course in Miracles, is not available for free online, but its workbook is. You can find it on the website for the Foundation for..."
"Here are two sets of statements from far-distant opposites in the climate change debate. The first is from Naomi Klein, who in her book This Changes Everything paints a bleak picture of a global socioeconomic system gone wrong: “There is a..."
"Voters who trust their government — and each other — are more supportive of ambitious welfare states than those who do not. Across nations, high levels of social trust correlate with high levels of social spending. The relationship between these..."
"With the presidential campaign under way, expect to hear a lot more about a shiny new toy of progressive economic thinking, “modern monetary theory.” It seems to be the only intellectual contortion that might allow candidates to promise..."
"“We don’t want to fight y’all. We’re not trying to go to jail.” That’s what A$AP Rocky, the 30-year-old New York City rapper, can be heard saying in a video of an encounter with strangers in Sweden that has ballooned into an international crisis."
"Israel’s top officials are considering denying Reps. Ilhan Omar and Rashida Tlaib entry to their country due to their outspoken, controversial criticism of Israel’s policy toward Palestinians, not to mention their slurs against American Jews as..."
"For most of our lives, we have been conditioned to share a piece of personal information without a moment’s hesitation: our phone number. We punch in our digits at the grocery store to get a member discount or at the pharmacy to pick up..."